Mr Mahesh from Ghansoli Navi Mumbai is bank officer and does lot of writing work. Pain in the wrist area in the line of thumb is because of over use activities of thumb. Thumb is most important digit of hand particularly dominant side (the story of Guru Drona and Eklavya in Mahabharat is known). The tendon moving the thumb passes through small tunnel and gets inflamed because of overuse. Patient has to avoid heavy activities which involve use of thumb. Many patients respond to local injection to reduce inflammation.